CURRICULUM VITAE
Place and date of birth: Sueca, Spain 10.09.1968, married, 2 children
EDUCATION
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1996 |
PhD Biology Instituto de Investigaciones Citologicas, University Valencia, Spain.1996, Dr. Erwin Knecht |
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1986-1991 |
Bachelor Biology-Biochemistry, University of Valencia (Spain) |
CURRENT POSITION(S)
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07/2014 |
present Max Planck Fellow, MPI for Brain Research, Frankfurt |
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01/2012 |
present Faculty Focus Program Translational Neurosciences (FTN), University Mainz |
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04/2011 |
present Full Professor. Chair Molecular and Cellular Neurobiology, Goethe University Frankfurt |
PREVIOUS POSITIONS
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04/2010 |
Call Full Professor Heinrich-Heine-Düsseldorf University/Director of the Institute of Cellular Biophysics in the Research Center Jülich GmbH of the Helmholtz Society. Declined. |
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11/2007-03/2011 |
Professor W2 Cluster of Excellence „Macromolecular Complexes” (CEF), Goethe University Frankfurt |
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08/2001-10/2007 |
Max Planck Independent Junior Research Group Leader. MPI of Neurobiology, Martinsried, Germany |
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07/1996-07/2001 |
Postdoctoral fellow, EMBL, Heidelberg, Developmental Biology Programme, Prof. Rüdiger Klein and Prof. Angel Nebreda. EU TMR Marie Curie Fellowship. |
FELLOWSHIPS AND AWARDS
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2014 |
Max Planck Fellow |
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2014 |
Member of the Academia Europaea |
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2012 |
Member of the German National Academy of Sciences Leopoldina |
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2012 |
Gutenberg Forschungskolleg (GFK) Fellow |
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2010 |
Paul Ehrlich and Ludwig Darmstädter Prize for Young Investigators |
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1996-1998 |
Training and Mobility of Researchers (TMR) EU |
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1997 |
Ph.D. Extraordinary Award by Valencia University |
INSTITUTIONAL RESPONSIBILITIES
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since 2013 |
Deputy-Speaker SFB 1080 “Molecular and Cellular Mechanisms of Neuronal Homeostasis" Mainz/Frankfurt |
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since 2012 |
Speaker GRADE-Brain (Frankfurt University). GRADE is the central research academy of the Goethe University. |
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since 2011 |
Vice-speaker of the Rhine-Main-Neuroscience Network (rmn2). |
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2009-2012 |
Board of Directors Cluster of Excellence Macromolecular Complexes |
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MEMBERSHIPS OF SCIENTIFIC SOCIETIES
Member: Academia Europaea, German Academy of Science Leopoldina, Marie Curie Fellowship Association, American Society for Biochemistry and Molecular Biology (ASBMB), German Neuroscience Society, German Society for Cell Biology, German Society for Biochemistry and Molecular Biology, Interdisciplinary Center for Neuroscience Frankfurt, Rhine-Main-Neuroscience Network (rmn2), Interdisciplinary Center for Membrane Proteomics Frankfurt (CMP), Cluster of Excellence “Macromolecular Complexes” (CEF), Cluster of Excellence “Cardio-Pulmonary System” (ECCPS)
RESEARCH INTERESTS
Developmental Neurobiology (synapse formation, dendritic arborization, cortex development); Synaptic plasticity; Neurovascular Link (instructive roles of vessels during neuronal development, Blood brain Barrier); Angiogenesis (Developmental retinal angiogenesis and pathological angiogenesis of solid tumors); Tumor Biology (progression and invasion of gliomas, tumor metastasis)
PUBLICATIONS
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Henze A-T, Garvalov BK, Seidel S, Cuesta A, Ritter M, Filatova A, Foss F, Dopeso H, Essmann CL, Maxwell PH, Reifenberger G, Carmeliet P, Acker-Palmer A# and Acker T# (2014) Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nature Communications, in press, #corresponding authors
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Garvalov BK, Foss F, Henze, AT, Bethani I, Gräf-Höchst S, Singh D, Filatova A, Dopeso H, Seidel S, Damm M, Acker-Palmer A# and Acker T# (2014) PHD3 regulates EGFR internalization and signaling in tumours Nature Communications, in press #corresponding author
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Geiger JC, Lipka J, Segura I, Hoyer S, Schlager MA, Wulf PS, Weinges S, Demmers J, Hoogenraad CC and Acker-Palmer A (2014) The GRIP1/14-3-3 pathway coordinates cargo trafficking and dendrite development. Developmental Cell 28:381-393
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Senturk A, Pfennig S, Weiss A, Burk K and Acker-Palmer A (2011) EphrinBs are essential components of the Reelin pathway to regulate neuronal migration. Nature 472: 356-60; 478:27
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Sawamiphak S, Seidel S, Essmann CL, Wilkinson G, Pitulescu ME, Acker T and Acker- Palmer A (2010) EphrinB2 regulates VEGFR2 function in developmental and tumour angiogenesis. Nature 465:487–491
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Essmann, C.L., Martinez, E., Geiger, J., Zimmer, M., Traut, M., Stein, V., Klein, R. and Acker- Palmer, A. (2008) Serine phosphorylation of ephrinB2 regulates trafficking of synaptic AMPA receptors. Nature Neuroscience 11: 1035 – 1043
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Segura, I., Eβmann, C. L., Weinges, S. and Acker-Palmer, A. (2007) Grb4 and GIT1 transduce ephrinB reverse signals modulating spine morphogenesis and synapse formation Nature Neuroscience 10: 301-310
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